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androgen receptor In this study we evaluated if different an
2018-10-31
In this study, we evaluated if different and distant anatomic regions of fat depots, albeit limited to the thoracic cavity, might reflect a heterogeneous array of biological, functional and ultrastructural features of ASCs. Our results support previous findings on putative differences between ASC po
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br Experimental Procedures br Acknowledgments br Introductio
2018-10-31
Experimental Procedures Acknowledgments Introduction Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), hold great promise in the fields of regenerative medicine and drug discovery. Although their practical u
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There are three possible explanations for our findings First
2018-10-31
There are three possible explanations for our findings. First, it is possible that the reprogramming process resulted in iPSCs that were solely derived from methylated FM fibroblasts and not of the unmethylated cells. This assumes that methylated FM fibroblasts were present in our culture, which acc
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Etonogestrel Supplier Articular cartilage is highly lubricio
2018-10-31
Articular cartilage is highly lubricious. Lubricin encoded by the PRG4 gene and glycosaminoglycans contribute to maintaining the low friction of cartilage and directly inhibit cell adhesion (Englert et al., 2005). Therefore, since the hiPSC-derived particles expressed PRG4, it is reasonable that the
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We previously reported that precursor cells
2018-10-31
We previously reported that precursor 4EGI-1 expressing the Myf5-Cre knockin driver give rise to a subset of white adipocytes in addition to brown adipocytes and skeletal muscle (Hung et al., 2014; Sanchez-Gurmaches and Guertin, 2014; Sanchez-Gurmaches et al., 2012; Tallquist et al., 2000). In youn
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Recently new genome modifying methods using
2018-10-31
Recently, new genome-modifying methods using sequence-specific endonucleases, such as zinc-finger nuclease (ZFN), transcription activator-like effector nuclease (TALEN), and clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9 (CRISPR/Cas9) systems, were developed o
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The genomic stability of hIPSCs has
2018-10-31
The genomic stability of hIPSCs has been extensively studied since this could be a major limitation for clinical applications (Aasen et al., 2008). Factors that affect the genomic integrity of stem buy salvinorin a include culture conditions, number of passages, and enzymatic and non-enzymatic diss
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Cyanine5.5 alkyne manufacturer These data are in agreement w
2018-10-31
These data are in agreement with prior studies demonstrating that hyaluronan levels play a critical role in determining the site of HSC lodgment/engraftment following transplantation (Avigdor et al., 2004; Ellis et al., 2007, 2009, 2011; Nilsson et al., 2003), and that HSC exhibit preferential engra
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Our study had two aims First we assessed the strength
2018-10-30
Our study had two aims. First, we assessed the strength of associations of several demographic, socioeconomic, and psychological variables on SSS, including race, sex, education, employment, income, depressive symptomatology, neighborhood satisfaction, and self-rated health. Considering all of these
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Another major goal of this study was
2018-10-30
Another major goal of this study was to evaluate the significance of multiple measures of glutamate receptor for shaping black-white disparities in physical health. Our results show that black-white differences in allostatic load vary by blacks’ skin tone. Specifically, with both self-identified ra
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br Data and methods br
2018-10-30
Data and methods Results Overweight was more common among males than among females (Table 1). The mean number of respondents per municipality was lower among the overweight compared with non-overweight; however, no difference was found by age. In both females and males, the overweight prevalen
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It is well established that work can
2018-10-30
It is well-established that work can influence health and wellbeing in both positive and negative ways (Ross & Mirowsky, 1995; LaMontagne & Keegel, 2009; van der Noordt, IJzelenberg, Droomers, & Proper, 2014). There also evidence that persons with disability have poorer health and wellbeing compared
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Because commercially available immunoassay presents limited
2018-10-30
Because commercially available immunoassay presents limited detection sensitivity on detecting low-abundance cancer biomarkers against the background of high-abundance zip inhibitor proteins. Recently, gold nanomaterials (GNPs) show unique optical properties and high surface areas, which have been
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Using the above equation Eq the
2018-10-30
Using the above equation (Eq. (2)), the surface concentration in our case was found to be 0.23×10−8mol/cm2. The diffusion coefficient (D) value of the redox species from the electrolyte to L/IL/ITO electrode was calculated using the Randles–Sevcik equation given by [33]where Ip is the peak current o
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To assess whether cytochrome C
2018-10-30
To assess whether cytochrome C release could also be detected in the supernatant of dofetilide exposed to different therapeutic agents, the MCF7 cells expressing Her2 were treated with drugs targeting this receptor (Trastuzumab with and without T-DM1). The responses shown in Fig. 2 show similaritie
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