• Common and rare SCN A variants may contribute to

  2019-06-12

  

  Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian

• br Materials and methods br Results br

  2019-06-12

  

  Materials and methods Results Discussion Our results demonstrated that patients who underwent ICD implantation and received 15J-DT exhibited evidence of myocardial damage as indicated by increased serum c-TNT and H-FABP levels. On the other hand, ≤10J-DT (9J or 10J) was associated with an a

• br Introduction Since Reekers and Bolia

  2019-06-11

  

  Introduction Since Reekers and Bolia introduced subintimal angioplasty, the trans-subintimal route has become the preferred technique to advance the guidewire through a totally occluded and often heavily calcified lesion, especially in the aortoiliac segment. The technical failure was seen in 20–

• According to Weitzman classification patients had

  2019-06-11

  

  According to Weitzman classification [43] 15 patients had a single ONJ lesion (4A) and 9 patients had multiple lesions (4B) or a “multifocal” lesion (Table 2). Six patients interrupted the treatment with O3 gas application for disease progression (five patients) and for fear of an experimental ther

• The so called driver hypothesis has

  2019-06-11

  

  The so-called driver ampar has been posited in the recent years. Optical mapping studies in isolated sheep hearts have suggested that at least some cases of AF can be maintained by high-frequency reentrant sources (rotors), usually located in the posterior LA, which result in spatially distributed

• Lead failures are classified as

  2019-06-11

  

  Lead failures are classified as either structural lead failures or electrical lead failures, and failures of 8F single coil leads are more frequently reported. Structural failures occur with a reported incidence of 14–34% and are evident as cable exteriorization in fluoroscopy studies [6,7]. Electri

• br Discussion HIV testing and linkage

  2019-06-11

  

  Discussion HIV testing and linkage to care are essential for fighting the HIV epidemic, and evidence-based methods for increasing coverage of testing and accelerating linkage to care are needed. We report that abbreviated counselling was as effective as full length counselling in reducing sexual

• br Since the launch of the

  2019-06-11

  

  Since the launch of the Every Newborn Action Plan (ENAP) at the World Health Assembly in 2014, and, in 2015, the launch of the UN Secretary General\'s second Global Strategy for Women\'s, Children\'s and Adolescents\' Health, there has been a renewed focus on improving newborn health globally. So

• Table shows the AF ablation procedure data

  2019-06-11

  

  Table 2 shows the AF ablation procedure data. The preoperative inspection consisted of transesophageal echocardiography and cardiac computed tomography (CT) in 79.9% and 80.8%, respectively; cardiac magnetic resonance imaging (MRI) was performed in only 1.1% of the patients. Two 3D mapping systems w

• br Does ambulatory monitoring prevent HF decompensation Whil

  2019-06-11

  

  Does ambulatory monitoring prevent HF decompensation? While vigilant monitoring of symptoms and signs (and BNP levels) is useful, it does not guarantee the accurate prediction of ADHF. On the other hand, frequent monitoring of some of these signs and symptoms and the use of external physiologica

• El tenor de aquella declaratoria se escribi con estas

  2019-06-10

  

  El tenor de aquella declaratoria se escribió con estas palabras: De este modo, y al margen de otras consideraciones que pudieran hacerse al respecto, para el caso que nos ocupa es importante significar que la iniciativa mexicana acabó tapiando las puertas de la onu sphingosine 1-phosphate receptor

• We have received funding from the Wellcome Trust to develop

  2019-06-10

  

  We have received funding from the Wellcome Trust to develop a global atlas of podoconiosis. We aim to advance new knowledge on the geographical distribution and spatial epidemiology of the disease. A first step in this work will be to establish the geographical absence of disease by applying an evid

• Previous health emergencies have shown that it can take time

  2019-06-10

  

  Previous health emergencies have shown that it can take time to organise global collective action and provide financing to the national and local level. In such situations, a global mechanism should offer a rapid injection of liquidity to affected countries. The World Bank\'s Pandemic Emergency Fina

• br Case A year old man was referred

  2019-06-10

  

  Case A 45-year-old man was referred for the management of sudden-onset tachycardia. He had experienced 3 episodes of palpitation attacks, lasting for a couple of hours each, during the last 6 months. A regular, wide QRS complex tachycardia (WCT) at 150beats/min with a prominent retrograde P wave

• The standard therapy for chordoma is excision Local recurren

  2019-06-10

  

  The standard therapy for chordoma is excision. Local recurrence, but not metastasis, is a major determinant of prognosis. Because local recurrence is related to initial surgical margin and intra-operative tumor cell contamination, achieving a safe margin is very important. Boriani [6] reported 153 c

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