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br Acknowledgments We thank all the
2019-04-15
Acknowledgments We thank all the ultramarathon runners who participated in this study and all the doctors, nurses, and emergency medical technicians who provided professional care at the ultramarathon race. We also thank our colleagues at Soochow University, Taipei, Taiwan and the Chinese Taipei
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Clinical history of patients with surface osteosarcoma depen
2019-04-15
Clinical history of patients with surface osteosarcoma depends on its grade of malignancy. In low grade lesions and especially in cPOS, symptoms are most often of prolonged duration [3]. However, in HGSO and DPOS—especially when the dedifferentiation is synchronous—clinical history is not distinguis
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br Conclusions It is now clear
2019-04-15
Conclusions It is now clear that a number of Protease Inhibitor Library are involved in inherited bradyarrhythmia. Recent genetic studies have demonstrated that inherited arrhythmia is attributable to many genes with diverse functions. While the precise underlying mechanisms remain to be elucida
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br En relaci n con este ltimo tipo de poes
2019-04-15
En relación con este último tipo de poesía, la escéptica, Baldomero Sanín Cano publica el artículo emblemático de la crítica modernista “Núñez, poeta” en 1888 en La Sanción. En este sentido, el crítico colombiano, David Jiménez afirma que este artículo “contiene ya los planteamientos fundamentales
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M s adelante del fragmento arriba citado de
2019-04-15
Más adelante del fragmento arriba citado de Memórias, hallamos otro en el que se aborda la cuestión de la insensibilidad. Graciliano la juzga extraña al igual que extraordinaria le parece la desaparición de los deseos sexuales: afirma que todos los sentidos desfallecían. Si son los sentidos los que
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A year old male was referred to our
2019-04-15
A 59-year-old male was referred to our hospital in cardiogenic shock. A 12-lead electrocardiogram showed abnormal Q-waves in V1–V4 leads and complete atrioventricular block; the patient was diagnosed with acute myocardial infarction (AMI) (Fig. 1). Upon arrival, the patient was unconscious, and his
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Los tres especialistas invitan a volver
2019-04-11
Los tres especialistas invitan a volver la mirada hacia la figura polémica de Las Casas y su Brevíssima relación desde nuestro complejo presente, para interpelarnos como lectores críticos del siglo xxi acerca de la dolorosa historia fccp de América Latina. Cronista que “ve la realidad tal cual e
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br Sin recetas para el crecimiento econ mico Dentro de
2018-11-15
Sin recetas para el crecimiento económico Dentro de la economía como disciplina se ha desarrollado un cuerpo analítico de teorías del crecimiento, mismas que parten de modelos y supuestos para explicar cómo y bajo qué mecanismos podría impulsarse el crecimiento del pib, el cual se interpreta como
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In recent years studies in finance and in econometrics
2018-11-15
In recent years studies in finance and in econometrics have tried to produce accurate forecasts of the term structure. Duffee (2002) uses the dynamic properties of affine models and concludes that his forecasts are dominated by the random walk model. The forecast underperformance of affine models st
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br Introduction The burden of malaria currently estimated at
2018-11-15
Introduction The burden of malaria, currently estimated at over 2 million episodes of clinical disease and 655,000 deaths annually (WHO, 2012), has exerted strong selection on the human genome, leading to the occurrence at high frequencies of a number of host-protective polymorphisms (Kwiatkowski
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However if we aimed to functionally characterize most CFTR
2018-11-15
However, if we aimed to functionally characterize most CFTR mutants, then it is also important to determine how to measure CFTR activity with a rare mutation when testing corrector candidates and how to take into consideration the genotype of the epithelial CF model cells. In other words, if we want
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br Materials and methods br
2018-11-15
Materials and methods Results Discussion The main MLN8237 of the present investigation, that there is a positive association between IPS-to-prefrontal functional connectivity with age was largely not borne out, though positive trends were identified in ROI analyses in the younger age group
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br Conflict of interest br Acknowledgements
2018-11-15
Conflict of interest Acknowledgements This work was supported by the Economic and Social Research Council (grant number ES/L003155/1). Introduction The attainment of flexible and effective emotion regulation skills during childhood is considered a key developmental task in support of psych
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Unexpectedly the inhibition of EGFR
2018-11-15
Unexpectedly, the inhibition of EGFR induces expression of keratinocyte differentiation markers. Keratinocyte proliferation and differentiation are mutually incompatible: apparently, inhibiting cell proliferation diverts the cells into a differentiation pathway and consequently certain differentiati
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br Introduction The epidermal permeability
2018-11-15
Introduction The epidermal permeability barrier is one of the most crucial protective functions of the skin and is primarily mediated by stratum corneum lipids and differentiation-related proteins. Stratum corneum lipids consist mainly of an equal molar ratio of cholesterol, fatty acids, and cera
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