• The imbalances in the current R D system were

  2019-04-16

  

  The imbalances in the current R&D system were the subject of the 2012 report of WHO\'s Consultative Expert Working Group on Research and Development (CEWG). The CEWG recommended a global binding agreement that provides a needs-driven and evidence-based framework for R&D, guided by the core principle

• kainate receptors Nakai et al showed that RTc

  2019-04-16

  

  Nakai et al. showed that RTc and Tpeak-end dispersion can be used to evaluate the spatial distribution of myocardial repolarization [15,16]. We measured RTc and Tpeak-end dispersion in the acute and chronic periods in the case reported herein. Both variables were increased during the acute period af

• The re treatment of metastatic bone

  2019-04-16

  

  The re-treatment of metastatic bone disease causing recurrent pain after an initial course of EBRT was seen to be feasible with a reasonable rate of symptom relief [13–19]. In echoing the ACR findings, the task force noted that the available data was derived from studies where re-treatment was not t

• Given the recognized effects of bisphosphonates in metastati

  2019-04-16

  

  Given the recognized effects of bisphosphonates in metastatic breast cancer [14,15] and that potential anticancer effects have been demonstrated in preclinical [16], translational [17], patients with cancer therapy-induced bone loss [18] and ABT263 based-studies [19,20] a number of clinical trials

• On the other hand several authors

  2019-04-16

  

  On the other hand, several authors reported that an ATP dabigatran etexilate mesylate injection could promote significant sympathomimetic effects. Biaggioni et al. suggested that intravenous ATP administration primarily activates afferent nerves via arterial (or carotid body) chemoreceptors or baror

• br In a detailed analysis using multiple data sources in

  2019-04-15

  

  In a detailed analysis using multiple data sources in this issue of , Emily Keats and colleagues show that Kenya made some progress in reducing maternal and newborn mortality between 2003 and 2015, and made greater progress in reducing child mortality between 1998 and 2015, after earlier increases

• We also found that the RBC folate level was

  2019-04-15

  

  We also found that the RBC folate level was significantly increased in individuals with the TT walk through compared to individuals with the CC genotype. The plasma folate concentration fluctuates in relation to diet, and is thus a useful dynamic measure that reflects recent nutritional uptake. Ther

• br Acknowledgments We thank all the

  2019-04-15

  

  Acknowledgments We thank all the ultramarathon runners who participated in this study and all the doctors, nurses, and emergency medical technicians who provided professional care at the ultramarathon race. We also thank our colleagues at Soochow University, Taipei, Taiwan and the Chinese Taipei

• Clinical history of patients with surface osteosarcoma depen

  2019-04-15

  

  Clinical history of patients with surface osteosarcoma depends on its grade of malignancy. In low grade lesions and especially in cPOS, symptoms are most often of prolonged duration [3]. However, in HGSO and DPOS—especially when the dedifferentiation is synchronous—clinical history is not distinguis

• br Conclusions It is now clear

  2019-04-15

  

  Conclusions It is now clear that a number of Protease Inhibitor Library are involved in inherited bradyarrhythmia. Recent genetic studies have demonstrated that inherited arrhythmia is attributable to many genes with diverse functions. While the precise underlying mechanisms remain to be elucida

• br En relaci n con este ltimo tipo de poes

  2019-04-15

  

  En relación con este último tipo de poesía, la escéptica, Baldomero Sanín Cano publica el artículo emblemático de la crítica modernista “Núñez, poeta” en 1888 en La Sanción. En este sentido, el crítico colombiano, David Jiménez afirma que este artículo “contiene ya los planteamientos fundamentales

• M s adelante del fragmento arriba citado de

  2019-04-15

  

  Más adelante del fragmento arriba citado de Memórias, hallamos otro en el que se aborda la cuestión de la insensibilidad. Graciliano la juzga extraña al igual que extraordinaria le parece la desaparición de los deseos sexuales: afirma que todos los sentidos desfallecían. Si son los sentidos los que

• A year old male was referred to our

  2019-04-15

  

  A 59-year-old male was referred to our hospital in cardiogenic shock. A 12-lead electrocardiogram showed abnormal Q-waves in V1–V4 leads and complete atrioventricular block; the patient was diagnosed with acute myocardial infarction (AMI) (Fig. 1). Upon arrival, the patient was unconscious, and his

• Los tres especialistas invitan a volver

  2019-04-11

  

  Los tres especialistas invitan a volver la mirada hacia la figura polémica de Las Casas y su Brevíssima relación desde nuestro complejo presente, para interpelarnos como lectores críticos del siglo xxi acerca de la dolorosa historia fccp de América Latina. Cronista que “ve la realidad tal cual e

• br Sin recetas para el crecimiento econ mico Dentro de

  2018-11-15

  

  Sin recetas para el crecimiento económico Dentro de la economía como disciplina se ha desarrollado un cuerpo analítico de teorías del crecimiento, mismas que parten de modelos y supuestos para explicar cómo y bajo qué mecanismos podría impulsarse el crecimiento del pib, el cual se interpreta como

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