• The virus tested in this

  2018-11-05

  

  The virus tested in this study is one of a family of genetically engineered viruses designed for specific infection and killing of cancer. These were meant as therapeutic agents. In preclinical studies, these viruses infect and kill many cancer cell lines, including many pancreatic cancer cell lines

• Gut Microbiome and Inflammatory Bowel Disease

  2018-11-05

  

  Gut Microbiome and Inflammatory Bowel Disease Modulation of Gut Microbiota in Obesity and Cardiometabolic Disorders Changes in gut microbiota are associated with metabolic disorders such as obesity, type 2 diabetes and cardiovascular risk factors. Patrice D. Cani (Brussels, Belgium), Willem M. d

• The lack of such stratification

  2018-11-05

  

  The lack of such stratification may underlie the inconsistent data from trials of LMWH for PMPC (Martinelli et al., 2012; Rodger et al., 2014) due to inclusion of heterogeneous disease mechanisms rather than a focus on those associated with a procoagulant mechanism. These findings also suggest that

• br Limitations and future lines of investigation

  2018-11-05

  

  Limitations and future lines of investigation This exploratory study has a series of limitations. First, the use of a sample of university students from a specific school can affect the external validity of the results. Second, we studied parental influence in only one region of Spain. Thus, a co

• Hypocretinergic activation during REM sleep

  2018-11-05

  

  Hypocretinergic activation during REM sleep is likely related to the activation that occur during certain patterns of somatomotor activity [50]. Although motor output is inhibited at the motoneuron level during REM sleep, supraspinal motor systems are very active during this state [60–62]. In fact,

• Our findings and those of Zhang challenge

  2018-11-05

  

  Our findings, and those of Zhang [34] challenge the conclusions from the recent Cochrane Review of “Long chain polyunsaturated purchase BMS-354825 supplementation in infants born at term [35]”. That review summarized outcomes from multiple clinical trials assessing whether supplementing infant form

• Considering the importance of sleep health many

  2018-11-05

  

  Considering the importance of sleep health, many studies have examined sleep quality as a marker of general health [28]. Sleep quality, which is a self evaluation of sleep, is considered more important than sleep quantity in the assessment of general health [29,30]. Poor sleep quality is associated

• br Materials and methods br Results br Discussion Discovery

  2018-11-05

  

  Materials and methods Results Discussion Discovery and characterization of cancer-associated markers effective in cancer diagnosis and treatment is a main focus in modern medicine. Several targets have been described [13,14]. Furthermore, we recently showed that the malarial VAR2CSA protein

• Data experimental design materials and methods br Experiment

  2018-11-03

  

  Data, experimental design, materials and methods Experimental design Two Brassica napus genotype under two kinds of P treatments, long-term low P stress and short-term P-free starvation, were conducted, and three time points were used in each P treatment. Total protein was extracted from roots o

• br Value of the data br Data br Experimental

  2018-11-03

  

  Value of the data Data Experimental design, materials and methods Acknowledgments This project was sponsored by a grant from the National Natural Science Foundation of China (31271159), a Maryland TEDCO Grant (2007-MSCRFE-0139-01), a Technology Foundation for Selected Overseas Chinese Sc

• GSK1324726A br Experimental design materials and

  2018-11-03

  

  Experimental design, materials and methods Secondary structure analysis of diluted HpFlgD (2mgmL−1) was performed by circular dichroism (CD) using a spectropolarimeter (Jasco Analytical Instruments) in the far UV region (190–260nm), Fig. 1. Afterwards, the data were deconvoluted using software C

• A downside in using a

  2018-11-03

  

  A downside in using a non-parametric model include the interpretation of partial dependencies which cannot be interpreted in any causative or absolute way, but only as descriptive (Berk et al., 2009). However, an exploratory analysis based on parametric techniques would not provide any useful causal

• Because more densely populated areas closer to

  2018-11-03

  

  Because more densely populated areas closer to towns generally obtain general development before rural and sparsely populated areas, doubts can be insulin receptor on the findings that development in other areas (Heltberg, 2004), would necessarily cause fuel switching. Electrification has been foun

• Notably a recent training study asked years old preschoolers

  2018-11-03

  

  Notably, a recent training study asked 6 years old preschoolers to learn grapheme to phoneme correspondence. Although these children had already acquired some letter knowledge (10 upper case letters and 5.8 lower case letters) prior to training, they did not possess neural tuning for words associate

• br Amygdala and striatum function in maturity The amygdala s

  2018-11-03

  

  Amygdala and striatum function in maturity The amygdala’s role in affective valuation has often been characterized from the point of view of aversive learning, and evaluating threats. Across species, the amygdala is strongly implicated in fear learning––i.e., associating stimuli or actions with a

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