• Tau helps assemble and stabilize microtubules In the

  2018-10-24

  

  Tau helps assemble and stabilize microtubules. In the CNS, several isoforms of tau are produced from a single gene by alternative splicing (Goedert et al., 1989). More than 40 pathogenic MAPT mutations have been described in more than 100 families with FTD (Cruts et al., 2012; Alzheimer Disease & Fr

• br Results br Discussion The interest

  2018-10-24

  

  Results Discussion The interest in directed cell-fate determination in stem cell biology and regenerative medicine has been increasing over the years. However, due to the complexity of GRNs, identification of cell-fate determinants and their functionally important subnetworks (GRN motifs) that

• Mixed populations of PSCs were also converted to naive

  2018-10-24

  

  Mixed populations of PSCs were also converted to naive PSCs in 2i + LIF medium without serum or to primed EpiLCs in bFGF + activin medium. EpiLCs induced from ESCs expressed only RFP, and the RFP+ EpiLCs were indistinguishable from EpiSCs in terms of morphology, gene expression patterns, epigenetic

• During normal development cytokine availability fluctuates p

  2018-10-24

  

  During normal development, cytokine availability fluctuates partly because HSCs have to move from one silybin to another, such as from FL to BM (Mazo et al., 2011). HSCs need to overcome apoptosis induced by cytokine fluctuation during normal development (Kohli and Passegue, 2014). Factors controll

• Our knowledge of human embryonic myeloid development and the

  2018-10-24

  

  Our knowledge of human embryonic myeloid development and the ontogeny of tissue-resident macrophages is much more limited due to the difficulty obtaining human embryos at such an early developmental stage (Ivanovs et al., 2011). That said, several human studies are consistent with those in the mouse

• As in mammals epithelial turnover in the

  2018-10-24

  

  As in mammals, epithelial turnover in the Drosophila intestine is also mediated by ISCs. Fly ISCs undergo cell division to renew themselves and give rise to transient cells, enteroblasts (EBs), which can differentiate into absorptive enterocytes (ECs) or secretory enteroendocrine (EE) cells. ISCs in

• However to increase emission efficiency these hot electrons

  2018-10-24

  

  However, to increase emission efficiency, these hot electrons have to reach the outer emitter boundary and to remain in its vicinity for a relatively long time without relaxation. According to recent studies [65,66], such possibility appears if the considered medium is composed by nanoparticles with

• Let us examine a thermodynamic model taking into account

  2018-10-24

  

  Let us examine a thermodynamic model taking into account the influence of interfacial tension on the reconstructive phase transition. Let us analyze an idealized case when the polycrystalline sample consists of spherical particles of radius R. Let us designate the Gibbs free methylguanine dna methyl

• One of the significant advantages

  2018-10-24

  

  One of the significant advantages of the PDT method is the fact that the photochemical reaction is accompanied by the fluorescence of both the photosensitizer and the singlet oxygen produced as a result of the reaction. The fluorescence analysis allows to perform in situ diagnostics, i.e., directly

• Introduction The main models used for describing the

  2018-10-24

  

  Introduction The main models used for describing the structure of woven materials are applicable only to a \"hard\" composite, with solid polymers, for example, hardened epoxy resin [1–6], acting as fillers. Geometric nonlinearity may be neglected for these materials [5,6], since deformations occur

• br For an isolated particle n where n is

  2018-10-24

  

  For an isolated particle, 0 = 0 = n0, where n0 is the concentration of charged particles in unperturbed plasma; besides, the thickness r0 of the perturbed region for that particle is not known in advance. The charge (the potential) of the particle in the steady-state case is determined by the cha

• br Conclusion br Introduction The

  2018-10-24

  

  Conclusion Introduction The interaction between cracks and interfaces of materials is an important problem in the mechanics of heterogeneous structures. The cracks growing in the process of such interaction can either be deflected by the interface with secondary debonding cracks forming or bre

• The notion that pets can

  2018-10-24

  

  The notion that pets can facilitate social capital goes beyond the more commonly investigated role of pets as a social icebreaker between strangers, or as a catalyst for social interaction (Hunt, Hart, & Gomulkiewicz, 1992; McNicholas & Collis, 2000; Messent, 1983; Newby, 1997; Robins, Sanders, & Ca

• br Methods br Results Table

  2018-10-24

  

  Methods Results Table 1 below presents baseline characteristics for intervention and matched control districts in 2010, the year before PBF began. While there are some differences in population size and the number of primary health facilities in matched districts, the number of facilities per

• br Introduction Wet scrubbers are important air

  2018-10-24

  

  Introduction Wet scrubbers are important air pollution control devices for cleaning large volumes of industrial effluent gas streams and they remove particulates and dangerous gases simultaneously by capturing into the droplets or pool of liquid and dissolving or absorbing into the liquid respect

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