• br Experimental Procedures Extended details outlining specif

  2018-11-02

  

  Experimental Procedures Extended details outlining specific steps and protocols can be found in the Supplemental Experimental Procedures. Author Contributions Acknowledgments Introduction Proximal spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder caused by t

• Several studies have linked expression

  2018-11-02

  

  Several studies have linked expression of CD44 and MMP14 to the CSC population. Data suggest common mechanisms regulating co-expression of these two genes; blockade of the ERK pathway suppressed expression of CD44 and MMP14 and inhibited invasiveness of cancer p2x7 antagonist (Tanimura et al., 2003)

• nmda receptor When it comes to the development of

  2018-11-02

  

  When it comes to the development of statistical radio engineering and radiophysics, Kotel\'nikov should be given credit where credit is due; we should point out, for historical accuracy, that in his monograph [2] he obtained, among other calculations, an example of a canonical decomposition, even th

• The results we obtained are also in a

  2018-11-02

  

  The results we obtained are also in a good agreement with the photoconductivity spectra under excitation by p- or s-polarized light in a structure similar to the one we examined, also containing wide doped QWs [10], where a broad SRT 1720 line associated with the 1→e1 and 1→2 transitions was also o

• The effect of rotation rate on the energy spectrum

  2018-11-02

  

  The effect of rotation rate on the salvinorin a spectrum of the vertical velocity component is illustrated by Fig. 5 (the monitoring point is located in the central horizontal plane, at a distance of 0.05Н from the adiabatic wall). The dimensionless oscillation frequency where f\' is the dimension

• br Data and methods br Results Table summarizes the characte

  2018-11-02

  

  Data and methods Results Table 1 summarizes the characteristics of the full sample and by gender. Table 2 shows results from 9 linear regression models of the three biomarker indices for the full sample and by gender. The coefficients associated with covariates (age, gender, race/ethnicity, a

• br Funding Source br Acknowledgements

  2018-11-02

  

  Funding Source Acknowledgements Data collection was supported by the Swedish Council for Working Life and Social Research, the Stockholm University Linnaeus Center for Integration Studies, and by a European Research Council Starting Grant [grant no. 263422] awarded to Jens Rydgren. Introduc

• The high prevalences of overweight

  2018-11-01

  

  The high prevalences of overweight and obesity found in the present study represent a worrying situation given the pilots were young adults and that excess weight is associated with many chronic diseases such as type II diabetes, arterial hypertension, stroke, cardiopathies, dyslipidemias and many o

• Intercalating molecules such as metal

  2018-11-01

  

  Intercalating molecules such as metal complexes based on ruthenium, osmium, iridium, platinum, cobalt [14–17] or organic compounds [18] may be a good method for electrochemical DNA probing because of their advantages such as reversibility of the redox reaction, chemical stability and simple function

• To generate energy for nanoscale systems ZnO

  2018-11-01

  

  To generate energy for nanoscale systems, ZnO based piezoelectric nanogenerators are an ideal source, especially in the case of small size and low power consumption batteries with a long life time. For a sustainable independent operation, a continuous power source is required and for this type of op

• Furthermore there is evidence for

  2018-11-01

  

  Furthermore, there is evidence for the role of transforming growth factor-β (TGF-β), a profibrotic cytokine, in the regulation of hyaluronan production (Heldin et al., 1989; Westergren-Thorsson et al., 1990; Dubaybo and Thet, 1990). Tissue injury, including cerebral injury, leads to significant incr

• A technique recently developed for in

  2018-11-01

  

  A technique recently developed for in vitro amplification of prions, the RT-QuIC (quaking-induced conversion) assay, is a highly sensitive and specific technique that can detect small amounts of prion-seeding activity (Takatsuki et al., 2015). In our study, the detection limit of the RT-QuIC assay w

• Here we sought to characterize the contribution of DGK

  2018-11-01

  

  Here we sought to characterize the contribution of DGKα and DGKζ to the generation of non-conventional bystander memory-like CD8+ T cell populations. We show that DGKζ deficiency, but not that of DGKα leads to increased output of CD44hiCD122hi CD8+ T FRAX597 and facilitates IL-2 and IL-15 responses

• br Semen collection and physiological tests Eleven adult

  2018-11-01

  

  Semen collection and physiological tests Eleven adult males of a standardized genetic origin [2] housed in the INRA PEAT experimental unit (Nouzilly, France) were collected twice a week. Sperm concentrations were determined [3] and individual ejaculates were diluted 1:1 in Beltsville Poultry Seme

• Analyses of the transition of the initial MA preparation int

  2018-11-01

  

  Analyses of the transition of the initial MAβ preparation into nOAβ and fibrillar Aβ (FAβ) over time are shown in Fig. 2. Fig. 2a shows that the Aβ Fraction Soluble decreases to 0.3 after 40 days, indicating the increasing checkpoint control of insoluble aggregates. This decrease in Fraction Solubl

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