• br Materials and Methods br

  2018-10-23

  

  Materials and Methods Results Discussion The thoracic aortic aneurysm in BAV patients frequently involves ascending aorta, where the SMCs are derived from the neural crest. In contrast, patients with BAV rarely have aneurysms involving the descending thoracic aorta, and the SMCs in this reg

• The vast majority of malaria infections in low

  2018-10-23

  

  The vast majority of malaria infections in low endemic settings are of low density (Imwong et al., 2016) but can contribute considerably to onward malaria transmission (Slater et al., 2015). However, the impact of current ACT and ACT-PQ on preventing onward malaria transmission from these low-densit

• The V SVZ derived neuroblasts migrating along blood vessels

  2018-10-23

  

  The V-SVZ-derived neuroblasts migrating along blood vessels assemble into chains similar to those in the RMS (Yamashita et al., 2006). The deletion of β1 integrin or laminin from neural cells impairs the chain formation in the RMS (Belvindrah et al., 2007; Emsley and Hagg, 2003). Our electron micros

• br Augmenting B Memory Cell Function can Worsen MS

  2018-10-23

  

  Augmenting B Memory Cell Function can Worsen MS Following the apparent efficacy of CD20-depleting agents in controlling MS (Hauser et al., 2008; Kappos et al., 2011; Sorensen et al., 2014), alternative methods of depleting B cells have been developed. One approach was the use of CD19 depleting pa

• In addition to the effect on early virus replication there

  2018-10-23

  

  In addition to the effect on early virus replication, there were also signs in our study that the tvrv vaccine reduced the immune hyperactivation normally associated with HIV/SIV infection and disease progression (Figs. 5 and 6). This is consistent with the virological findings as the immune scarrin

• Since WNK overexpression accelerated expression of adipogeni

  2018-10-23

  

  Since WNK4 overexpression accelerated butein of adipogenic genes (Fig. S7), we expected the overexpression of WNK4 in adipocytes would cause the phenotypes opposite to those in WNK4−/− mice. We first checked the WNK4 protein levels in the adipose tissues of WNK4D561A/+ and WNK4-Tg mice, which we hav

• The impaired complex I function may lead to

  2018-10-23

  

  The impaired complex I function may lead to increased oxidative injury, calcium dysregulation and mitochondrial driven cell death (). Thus, a further downregulation of electron transport flux through a damaged/diseased electron transport chain may reduce cell injury (). This concept had previously o

• In sum we report that TNMD

  2018-10-23

  

  In sum, we report that TNMD/Tnmd is a mechanosensitive gene vital for optimal running performance, proper tendon cotransporter to running and maintenance of structurally and functionally integral collagen fibrils. Materials and Methods Results Discussion Mechanical stimuli are important f

• br Cutaneous Microbiome in Inflammatory Skin Diseases The

  2018-10-23

  

  Cutaneous Microbiome in Inflammatory Skin Diseases The skin acts as an important interface between the organism and the external environment, but also represents an ecosystem providing distinct niches for microbial communities. Next-generation-sequencing approaches used to characterize the cutane

• The present study by Rouers and coworkers

  2018-10-23

  

  The present study by Rouers and coworkers found that within EC there was a much higher frequency of HIV Env-specific memory B cell responders compared to patients that have been rendered aviremic through the use of cART (). Remarkably, this was despite the fact that members of the EC cohort were inf

• The decrease in Ab levels is undoubtedly caused

  2018-10-23

  

  The decrease in Ab levels is undoubtedly caused by general deterioration of the immune response, which is well documented, not only in terms of decreased CD4+ T-cell counts but also in proliferative responses (Imami et al., 2013; Lewis et al., 2014). Here, we sought to quantify and characterize peri

• br Acknowledgements br Value of the data

  2018-10-23

  

  Acknowledgements Value of the data We provide a standard proteomic dataset based on a highly complex sample (yeast lysate) spiked with different levels of a second calibrated protein mixture of medium complexity (UPS1 standard, 48 proteins), that can be used to statistically evaluate label-fre

• br Experimental design materials and methods br Acknowledgme

  2018-10-23

  

  Experimental design, materials and methods Acknowledgments This work was supported by the project “Seeding production of eel Anguilla japonica by artificial induction of sexual maturation” (R2016011) of the NIFS, Korea, and the Export Strategical Item of KIMST, Korea. Data The dataset pres

• br Acknowledgements br Data The

  2018-10-23

  

  Acknowledgements Data The front panel and block diagrams constituting the LabVIEW® Virtual Instrument (VI) are shown (Figs. 1–4) to demonstrate the software/programmatic component of the pHstat system. Figs. 1 and 2 depict the front panel of the two functionalities of the VI. The front panel

• sp was determined based on the method of continuous

  2018-10-22

  

  Аsp was determined based on the method of continuous acceleration registration during reverse ballistic experiments. In order to determine the specific displacement work of material targets, the experiments on penetration of undeformable projectile (d0 = 0.005 m and cyclic adenosine monophosphate

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