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br Materials and methods br Results br
2018-10-24

Materials and methods Results Discussion riPSCs are typically generated and cultured on MEF feeders (Liu et al., 2008). Feeders are sufficient to support rhesus iPSC long-term maintenance. However, this approach is too labor intensive for large-scale culture. Optimization of this culture sy
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Although there is strong clinical support for developing
2018-10-24

Although there is strong clinical support for developing cellular therapies, and the use of such therapies is already reaching clinical translation (Götherström et al., 2014), ethical issues associated with the collection and use of fetal tissue for research and therapy still remain. Concerned polit
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br Heteroplasmy mitochondrial segregation and disease
2018-10-24

Heteroplasmy, mitochondrial segregation and disease In an individual with a mitochondrial disease, different cells or populations may have differing amounts of the mutant mitochondria, ranging from complete homoplasmy – individuals with all mutant mitochondrial DNA as occurs in Leigh\'s Syndrome
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c Kit RP http www apexbt com media diy
2018-10-24

c-Kit+ RPCs are distributed from the central to the peripheral regions of the retina, but not in the ciliary bodies, which were previously proposed to house retinal progenitors (Cicero et al., 2009; Martinez-Navarrete et al., 2008). These data suggest that c-Kit+ RPCs are a distinct population of bu
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The antitumor potential of iNKT cells has
2018-10-24

The antitumor potential of iNKT EZ Cap Reagent GG (3\' OMe) has been demonstrated in several clinical trials (Chang et al., 2005; McEwen-Smith et al., 2015; Motohashi et al., 2006, 2009; Nicol et al., 2011; Richter et al., 2013; Song et al., 2009; Uchida et al., 2008; Yamasaki et al., 2011). Infilt
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br Introduction The neocortex also called the dorsal
2018-10-24

Introduction The neocortex, also called the dorsal cortex, is an immensely complex mammalian gaba receptor structure that controls higher cognitive functions, such as problem solving and reasoning, sensory perception, emotional processing, and attention. The developing neocortex is populated by
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Tau helps assemble and stabilize microtubules In the
2018-10-24

Tau helps assemble and stabilize microtubules. In the CNS, several isoforms of tau are produced from a single gene by alternative splicing (Goedert et al., 1989). More than 40 pathogenic MAPT mutations have been described in more than 100 families with FTD (Cruts et al., 2012; Alzheimer Disease & Fr
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br Results br Discussion The interest
2018-10-24

Results Discussion The interest in directed cell-fate determination in stem cell biology and regenerative medicine has been increasing over the years. However, due to the complexity of GRNs, identification of cell-fate determinants and their functionally important subnetworks (GRN motifs) that
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Mixed populations of PSCs were also converted to naive
2018-10-24

Mixed populations of PSCs were also converted to naive PSCs in 2i + LIF medium without serum or to primed EpiLCs in bFGF + activin medium. EpiLCs induced from ESCs expressed only RFP, and the RFP+ EpiLCs were indistinguishable from EpiSCs in terms of morphology, gene expression patterns, epigenetic
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During normal development cytokine availability fluctuates p
2018-10-24

During normal development, cytokine availability fluctuates partly because HSCs have to move from one silybin to another, such as from FL to BM (Mazo et al., 2011). HSCs need to overcome apoptosis induced by cytokine fluctuation during normal development (Kohli and Passegue, 2014). Factors controll
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Our knowledge of human embryonic myeloid development and the
2018-10-24

Our knowledge of human embryonic myeloid development and the ontogeny of tissue-resident macrophages is much more limited due to the difficulty obtaining human embryos at such an early developmental stage (Ivanovs et al., 2011). That said, several human studies are consistent with those in the mouse
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As in mammals epithelial turnover in the
2018-10-24

As in mammals, epithelial turnover in the Drosophila intestine is also mediated by ISCs. Fly ISCs undergo cell division to renew themselves and give rise to transient cells, enteroblasts (EBs), which can differentiate into absorptive enterocytes (ECs) or secretory enteroendocrine (EE) cells. ISCs in
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However to increase emission efficiency these hot electrons
2018-10-24

However, to increase emission efficiency, these hot electrons have to reach the outer emitter boundary and to remain in its vicinity for a relatively long time without relaxation. According to recent studies [65,66], such possibility appears if the considered medium is composed by nanoparticles with
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Let us examine a thermodynamic model taking into account
2018-10-24

Let us examine a thermodynamic model taking into account the influence of interfacial tension on the reconstructive phase transition. Let us analyze an idealized case when the polycrystalline sample consists of spherical particles of radius R. Let us designate the Gibbs free methylguanine dna methyl
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One of the significant advantages
2018-10-24

One of the significant advantages of the PDT method is the fact that the photochemical reaction is accompanied by the fluorescence of both the photosensitizer and the singlet oxygen produced as a result of the reaction. The fluorescence analysis allows to perform in situ diagnostics, i.e., directly
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