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Ultrasound is an acoustic wave with a
2021-08-27
Ultrasound is an acoustic wave with a frequency >20 kHz that needs a medium to propagate [20]. Accompanied by the spread of an ultrasonic wave, a series of alternating cycles of compression and rarefaction emerge in the liquid medium. During the rarefaction cycle, microbubbles are formed because of
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Recently Zhao et al have been
2021-08-27
Recently, Zhao et al. have been carried out a study to investigate the relationship between eNOS-4b/a polymorphism and the risk of LCPD in a Chinese population. Their results demonstrated that eNOS polymorphisms may be involved in the etiology of LCPD. However, the number of studies conducted to exa
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In terms of its protease activity
2021-08-27
In terms of its protease activity, MME has a broad range of substrates being able to target glucagon, bradykinin, GLP1, and several other Ac-IETD-AFC of circulating small molecules [25]. MME has been shown to target free insulin B-chain [32], although whether MME could target and degrade the insuli
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GPR also known as EBI is a
2021-08-26
GPR183 (also known as EBI2) is a Gαi-coupled seven-transmembrane chemotactic receptor. It is highly expressed on follicular B cells, CD4+ dendritic cells (DCs), and CD4+ T cells but is downregulated on germinal center (GC) Teicoplanin in secondary lymphoid organs and controls cell migration to achi
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aristocort australia br Materials and methods br Results
2021-08-26
Materials and methods Results and discussion Conclusions Data about the ability of non-conventional ligands to operate class-A GPCRs have been accumulating. Specifically, increasing evidence indicates that oxysterols, oxidized derivatives of cholesterol, are involved in many activities that
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Structural changes within the heteromer induced
2021-08-26
Structural changes within the heteromer induced by agonist administration show a high level of complication. The presented results obtained in quantitative FLIM-FRET measurements with two selective ligands match the qualitative conclusions indicated by changes in the intracellular calcium level. The
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To study the role of DNA PK in
2021-08-26
To study the role of DNA–PK in the response to replication arrest, we used the DNA replication inhibitor aphidicolin (APH). APH, a mycotoxin isolated from Cephalosporium aphidicola, inhibits DNA replication by interacting with the replicating DNA polymerase α (pol α). APH specifically inhibits the a
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Methylpiperidino pyrazole Our observation that FAK is
2021-08-26
Our observation that FAK is downregulated in vascular smooth muscle Methylpiperidino pyrazole on fibrillar collagen confirms observations reported for other cell types [14]. However, unlike the results reported previously [14], our work suggests that matrix rigidity per se does not determine FAK dow
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In summary our data show a novel
2021-08-26
In summary, our data show a novel mechanism: CPD-mediated autoprocessing of C difficile toxins regulates their proinflammatory activities. Thus, our study provides a new understanding of the molecular mechanisms of the pathogenesis of C difficile toxins and insights into designing new therapeutics
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The CPA parameters of SO were calculated based on Eq
2021-08-26
The CPA parameters of SO2 were calculated based on Eq. (11) using the vapor pressure and saturated liquid density data of SO2 over the reduced temperature range of 0.55 to 0.9. All of the data used were taken from the NIST database [53]. The resulting CPA parameters of SO2 are presented in Table S1
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Fatty acid oxidation plays a crucial role in maintaining
2021-08-26
Fatty AZD 3965 β-oxidation plays a crucial role in maintaining body energy homoeostasis mainly during catabolic states. It mainly occurs in mitochondria and involves a cyclical series of reactions that result in the shortening of fatty acids. Fatty acids comprise an efficient source of energy that
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Nile tilapia Oreochromis niloticus is an important
2021-08-26
Nile tilapia (Oreochromis niloticus) is an important species farmed worldwide (Doan et al., 2018). Lipid-rich diets are commonly used in Nile tilapia aquaculture to reduce feed cost, but impair lipid homeostasis (Huang et al., 2016). Therefore, it is important to determine whether forskolin can stim
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An increased CK activity was
2021-08-26
An increased CK2 activity was found in septal neuronal Protease Inhibitor Cocktail (EDTA-Free, 100X in DMSO) dissected from rat embryos after hypoglycemia [36]. These data indicated that CK2 activity is not only regulated by insulin but also by the glucose concentration. One essential step in insu
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Recent studies have shown that some CLC genes participate in
2021-08-26
Recent studies have shown that some CLC genes participate in plant salt tolerance and have speculated that they function by mediating Cl− transport across the tonoplast. For instance, AtCLCc, a vacuolar anion transporter, is shown to be involved in the regulation of stomatal movement and to contribu
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Finally we have determined for the first time that aromatase
2021-08-26
Finally, we have determined for the first time that aromatase enzyme activity is necessary to observe IGF-1-dependent Disulfiram receptor activation. Neuroestrogen synthesis has been shown to be important for the maintenance of synaptic spine density in hippocampal slice cultures (Kretz et al., 2004
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