• Previous studies from our laboratory in

  2020-04-24

  

  Previous studies from our laboratory in CD1 mice using the incisional postoperative pain model have shown that the incision induces significant mechanical postoperative hyperalgesia lasting between 7 and 10days, with peak effect between 4h-2days (Cabañero et al., 2009a, Cabañero et al., 2009b, Campi

• Sterol regulatory element binding proteins SREBPs regulate

  2020-04-24

  

  Sterol regulatory element binding proteins (SREBPs) regulate transcription of genes involved in fatty BMX-IN-1 synthesis [38] (fatty acid synthase, and acetyl-CoA carboxylase) as well as triglyceride synthesis [39]. SREBP-1 protein levels are reduced in 3T3-F442A adipocytes [40] and increased in pri

• POE specialises Rogers definition of engineering to systems

  2020-04-24

  

  POE specialises Rogers\' definition of engineering [37] to systems engineering as: As such, systems engineering becomes a problem solving exercise, the problem being, given a physical environment E, to find the system S that LX-1031 meets a real-world need N to the satisfaction of a group of stake

• Although it remains an unsettled issue evidence favors that

  2020-04-22

  

  Although it remains an unsettled issue, evidence favors that the endothelin ETA Quetiapine Fumarate may play a more important pathological role. While both endothelin ETA and ETB receptors are found in most tissues, endothelin ETA receptor is the predominant receptor responsible for the vasoconstri

• The elastase induced injury model

  2020-04-22

  

  The elastase-induced injury model has been shown to produce airspace enlargement, and increases in lung volume and compliance that are similar to those observed in human patients (Hantos et al., 2008, Hamakawa et al., 2011). Thus, this model, which has been used to study emphysema, should be adequat

• Our study showed that parental morphine

  2020-04-22

  

  Our study showed that parental morphine exposure in the adulthood is associated with an increased tendency toward morphine consumption in F1 but not F2 male offspring. Thus, it seems that trans-generational effects of parental morphine consumption disappear in the second generation. In support of ou

• Interestingly some drugs have been shown to be effective in

  2020-04-22

  

  Interestingly, some drugs have been shown to be effective in the regulation of cytokine production (such as IL-2, IL-10, IL-27, IL-35, IL-37 and transforming growth factor-β, TGF-β) and, therefore, having a key role in the management of certain inflammatory-based clinical conditions (Banchereau et a

• In mice our EBI EGFP reporter showed

  2020-04-22

  

  In mice, our EBI2EGFP reporter showed that EBI2 is expressed consistently in naive T helper cells. Already single positive CD4+ thymocytes express EBI2 (not shown). In effector and regulatory T cells in naive mice, the percentage of EBI2 expression was lower (∼40%). Like others (Liu et al., 2011), w

• br Introduction Addiction to opioids such as

  2020-04-22

  

  Introduction Addiction to opioids such as morphine is a chronic disorder that affects the mesocorticolimbic dopaminergic pathway in the brain. Activation of the pathway ultimately leads to dopamine release in the nucleus accumbens (NAc) (Di Chiara et al., 1998) and stimulation of dopamine recepto

• apramycin It seems plausible that this ESC driven

  2020-04-21

  

  It seems plausible that this ESC-driven effect relies on a paracrine signaling. Numerous studies showed that the Fgf4 (fibroblast growth factor 4)/MAPK (mitogen-activated protein kinase) pathway is involved in PE differentiation in mouse apramycin (Chazaud et al., 2006), (Frankenberg et al., 2011),

• Among the down regulated genes were several of interest Coro

  2020-04-21

  

  Among the down-regulated genes were several of interest. Coronin2a (Coro2a), a component of the nuclear receptor co-repressor complexes, contributes to de-repression of inflammatory response genes (Huang et al., 2011). Mill1, an MHC family member expressed in hair follicles, represses wound healing

• Elastase belongs to chymotrypsin family of proteases and it

  2020-04-21

  

  Elastase belongs to chymotrypsin family of proteases and it is responsible for the breakdown of elastin and other proteins, such as collagen and fibronectin, which are fundamental for the ECM elastic properties (Imokawa and Ishida, 2015). Misregulations of this enzyme are involved in skin ageing pro

• Possibly there are similarities among

  2020-04-21

  

  Possibly there are similarities among euphorb plant species but extraction of the cccp mitochondria australia present in the microsomal fraction is needed for testing their preferences for substrates. Although R. communis, E. lathyris and E. lagascae belong to the same family, the DGAT activity of

• Just as Dorin et al and Nguyen et al

  2020-04-21

  

  Just as Dorin et al. [2] and Nguyen et al. [3] write in regard to their models, our static model can be used to estimate the affinities of DL-α-Hydroxyglutaric acid disodium salt to albumin and CBG. Dorin et al. [2] estimates the K, but not K, since they find that their model is not particular sensi

• It is well known that Doxorubicin induced cardiotoxicity occ

  2020-04-20

  

  It is well known that Doxorubicin-induced cardiotoxicity occurs via p53-mediated apoptosis (Lorusso et al., 2007). However, there are few studies elucidating the mechanism of HFS induced by PLD. We found that PLD induces keratinocyte apoptosis in a very low dose, and the damage induced by PLD cannot

15320 records 803/1022 page Previous Next First page 上5页 801802803804805 下5页 Last page