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Notably it is also reported that changes in lipoprotein
2019-04-23
Notably, it is also reported that changes in lipoprotein lipase (LPL) activity, HSL activity, and cAMP accumulation in WAT and BAT after ethanol exposure differ depending on the dose and route of ethanol exposure and tissue type. Moreover, a recent study also found that chronic feeding plus alcohol
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br In their Comment on
2019-04-23
In their Comment on the use of antenatal corticosteroids to reduce preterm infant deaths, Kishwar Azad and Anthony Costello advise “extreme caution” before scale-up in low-income settings. They emphasise maternal sepsis as a concern but cite only one trial in which dexamethasone resulted in a sign
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Estimates of life expectancy are
2019-04-23
Estimates of life expectancy are of obvious importance to people with HIV-1, and are essential to monitor and predict the progress of the HIV/AIDS epidemic and to plan health services. The Rwandan study reported by Sabin Nsanzimana and colleagues in is the first from sub-Saharan Africa to focus on t
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br The west African outbreak of Ebola virus disease
2019-04-23
The 2014–15 west African outbreak of Ebola virus disease is unprecedented in scale, especially in Sierra Leone, which as of May 15, 2015, had reported 8598 confirmed cases and 3538 confirmed Ebola-related deaths. Sierra Leone\'s response to this emergency has been compromised by a fragile health s
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br As mantenedoras e os mantidos
2019-04-23
As mantenedoras e os mantidos São as organizações sociais que gerenciam os hospitais, determinam as políticas internas itk inhibitor serem seguidas, estipulam como devem ser os atendimentos dentro das normas contratuais e diretrizes dos sus, negociam os contratos de gestão e seus aditamentos, etc
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Conflict of interest br Authors contributions br Acknowledgm
2019-04-23
Conflict of interest Authors׳ contributions Acknowledgments This work was supported by grants from the Associazione Italiana Lotta alle Leucemie, Linfoma e Mieloma (AIL) – Sezione ‘Luciano Pavarotti’ Modena-ONLUS (to FF and LP) and from the Associazione Italiana per la Ricerca sul Cancro (AIR
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Notwithstanding issues of equity improvement of
2019-04-23
Notwithstanding issues of equity, improvement of research capacity in LMICs has practical benefits. People working and living in LMICs are better placed to define issues of importance to their populations than are people living thousands of miles away in HICs—who often fund research based on their o
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Many previous studies have reported that activation of p ind
2019-04-23
Many previous studies have reported that activation of p38 induces cell death of hippocampal neurons rather than cell survival by using p38-specific inhibitors [18,[25], [26], [27], [28], [29], [30], [31], [32]]. A plausible explanation for this discrepancy is that we used both a cell-permeable p38
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Cardiac troponin I cTnI is a well established
2019-04-23
Cardiac troponin I (cTnI) is a well-established, sensitive, and specific marker of myocardial injury. However, evidence indicates that unrecognized myocardial injury may be occurring with certain conditions such as sepsis without acute coronary ischemic event, which demonstrate elevated cTnI levels.
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After CRT D implantation the QRS
2019-04-23
After CRT-D implantation, the QRS duration decreased to 122ms (Fig. 2), and the cardiac dyssynchrony improved. However, 5 days after implantation, atrial flutter (AFL) and electrical storm presenting as frequent VT were seen. As shown in Fig. 3A, the VT was initiated by a premature ventricular compl
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br Introduction Bone marrow adipocytes
2019-04-22
Introduction Bone marrow adipocytes are one of the most abundant cell types found in bone marrow tissue. They constitute approximately 15% of the bone marrow volume in young adults, rising to 60% by the age of 65 years old [1]. Previously considered as inert space filling cells with little biolog
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br Discussion Valproic acid is a potent inhibitor
2019-04-22
Discussion Valproic bet bromodomain is a potent inhibitor of histone deacetylases (HDAC). It can modify the structure of chromatin allowing recruitment of transcription factors to restore epigenetically suppressed genes. Valproic acid has been shown to possess antiproliferative activity and to o
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The primary tool in the pharmacological management of PTSD
2019-04-22
The primary tool in the pharmacological management of PTSD is the use of selective serotonin reuptake inhibitors [55,56], but positive response rates are generally limited. In addition, non-pharmacological treatment such as CBT has been shown to be effective for PTSD [57]. Psychological distress
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En diversos lugares de M
2019-04-22
En diversos lugares de México, como en Guerrero, el Valle del Mezquital, la región de Actopan, etc., según confirman las publicaciones del Instituto Nacional de Antropología e Historia de la ciudad de México, la creencia de que los huesos de los antepasados se convierten en piedras con propiedades e
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Actualmente los movimientos sociales est n desarrollando ya
2019-04-22
Actualmente, los movimientos sociales están desarrollando ya una importante función de “representación expresiva”, y transmiten puntos de identificación en una sociedad fragmentada que impugna al Estado y YO-01027 la sociedad sobre la exclusión y las desigualdades existentes. Justamente, el segundo
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