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CaMKII phosphorylation of L type Ca channels alters channel
2019-06-21
CaMKII phosphorylation of L-type Ca2+channels alters channel gating by increasing open probability. CaMKII increases the window current of ICa-L, increasing the probability of the channels reopening during phase 2 Y 134 and predisposing to early afterdepolarizations. Recently identified phosphoryla
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br Discussion The differential diagnosis of
2019-06-21
Discussion The differential diagnosis of ATA with a constant CS activation sequence following PV isolation for AF includes (a) AF originating from a non-PV focus [1], (b) focal ATA, and (c) macro-reentrant AFL of LA or RA origin [2–4]. First, the proximal-to-distal CS activation sequence during t
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br Material and methods The study subjects were
2019-06-21
Material and methods The study subjects were 28 consecutive patients with organic VU 591 hydrochloride disease who underwent ICD implantation for the secondary prevention of sudden cardiac death, based on the indications for ICD implantation in the European Society of Cardiology׳s guidelines [12
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br History of cholesterol and bile acid research Bile
2019-06-21
History of cholesterol and bile c-di-AMP research Bile is a yellow, brownish, or olive-green liquid that is composed primarily of water, organic solutes (such as lipids), inorganic salts, and some proteins. In bile, cholesterol, phospholipids, and bile acids are three major lipids, and bile pigm
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La representaci n colectiva de los ind genas
2019-06-21
La representación colectiva de los indígenas se caracteriza por el tono apologético, idealizado, en el que el uso abundante de los superlativos contribuye Tolvaptan resaltar hiperbólicamente la naturaleza pacífica del nativo como “buen salvaje”: Siguiendo el esquema de las oposiciones binarias, Las
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HCV does not kill the cells
2019-06-20
HCV does not kill the DPNI-caged-GABA Supplier it infects, but triggers an immune-mediated inflammatory response (hepatitis) that either rapidly clears the infection or slowly destroys the liver, causing the development of HCC and cirrhosis. The outcome is largely determined by the efficiency of the
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The authors would like to
2019-06-20
The authors would like to thank Ms. Fang-Ju Sun for her help with statistical analysis. This study was supported by a research grant from Mackay Memorial Hospital (MMH10466). Introduction Cancer of the HBX 41108 (CC) is the second most common cancer affecting women worldwide, and about 86% of C
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Finally MM patients have accelerated bone loss when compared
2019-06-20
Finally, MM patients have accelerated bone loss when compared to age-matched controls. Bone mineral density is decreased in patients with MM as well as in patients with monoclonal gammopathy of undetermined significance (MGUS) [19,20], a clinically benign condition defined by a low level of monoclon
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E3330 The ability of tumors to progress to
2019-06-20
The ability of tumors to progress to more malignant phenotypes depends on tumor microenvironment. Blood capillaries, made up of endothelial cells, are usually static under physiological conditions but are induced to proliferate by direct exposure to angiogenic factors, for instance, vascular endothe
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En Introducci n Bases filos
2019-06-20
En “Introducción. Bases filosóficas del poema” (11-34), Evodio Escalante une los tres hilos de las grandes madejas que considera fundamentales para entender el origen y los alcances de este poema filosófico: Heidegger, Nietzsche y de Gorostiza. La presentación es gradual y va de la mera conexión ane
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After CRT D implantation the QRS duration decreased to ms
2019-06-20
After CRT-D implantation, the QRS duration decreased to 122ms (Fig. 2), and the cardiac dyssynchrony improved. However, 5 days after implantation, atrial flutter (AFL) and electrical storm presenting as frequent VT were seen. As shown in Fig. 3A, the VT was initiated by a premature ventricular compl
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Upon examining his previous hospital records from years prio
2019-06-20
Upon examining his previous hospital records from 4 years prior, we found that he was diagnosed with acute heart failure at the second hospitalization 1 week after catheter ablation for atrial fibrillation. His symptoms and chest radiographic findings had improved by standard therapy for heart failu
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br Conclusions br Conflict of interest br Introduction br Ca
2019-06-20
Conclusions Conflict of interest Introduction Case report A 26-year-old woman in the 19th week of her first pregnancy presented with a chief complaint of palpitations. Electrocardiogram (ECG) showed sustained AT with heart rate (HR) of 180bpm. The P wave morphology was positive in the in
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More recently Brugada et al
2019-06-20
More recently, Brugada et al. [131]. used flecainide to identify the full extent of low-voltage electrogram activity in the anterior RV and RVOT and targeted this region for RFA. In all 14 BrS patients, RFA eliminated abnormal bipolar electrograms, normalized ST-segment elevation on right precordial
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(+)-Usniacin This time last year to coincide
2019-06-19
This time last year, to coincide with (March 9), launched a to highlight the rising burden of kidney disease and to encourage research partnerships to address gaps in knowledge and care, including the affordability of such care. Nephrology research and collaboration has come a relatively long way
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